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中华移植杂志(电子版) ›› 2020, Vol. 14 ›› Issue (03) : 196 -200. doi: 10.3877/cma.j.issn.1674-3903.2020.03.014

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综述

肾移植后糖尿病危险因素分析及管理
余红梅1, 郝卓文1, 孙功鹏1, 范志鹏1, 董礼1, 叶啟发2,()   
  1. 1. 430071 武汉大学中南医院肝胆疾病研究院 武汉大学移植医学中心 移植医学技术湖北省重点实验室
    2. 430071 武汉大学中南医院肝胆疾病研究院 武汉大学移植医学中心 移植医学技术湖北省重点实验室;410013 长沙,中南大学湘雅三医院移植中心 卫生部移植医学工程技术研究中心
  • 收稿日期:2020-01-21 出版日期:2020-06-25
  • 通信作者: 叶啟发
  • 基金资助:
    湖北省技术创新专项(2016ACA155)

Research progress and risk management of post transplantation diabetes mellitus in renal transplantation recipients

Hongmei Yu1, Zhuowen Hao1, Gongpeng Sun1, Zhipeng Fan1, Li Dong1, Qifa Ye2,()   

  1. 1. Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University & Hubei Key Laboratory of Transplant Medical technology on Transplantation, Wuhan 430071, China
    2. Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University & Hubei Key Laboratory of Transplant Medical technology on Transplantation, Wuhan 430071, China; The 3rd Xiangya Hospital of Central Sourth University & Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha 410013, China
  • Received:2020-01-21 Published:2020-06-25
  • Corresponding author: Qifa Ye
  • About author:
    Corresponding author: Ye Qifa, Email:
引用本文:

余红梅, 郝卓文, 孙功鹏, 范志鹏, 董礼, 叶啟发. 肾移植后糖尿病危险因素分析及管理[J]. 中华移植杂志(电子版), 2020, 14(03): 196-200.

Hongmei Yu, Zhuowen Hao, Gongpeng Sun, Zhipeng Fan, Li Dong, Qifa Ye. Research progress and risk management of post transplantation diabetes mellitus in renal transplantation recipients[J]. Chinese Journal of Transplantation(Electronic Edition), 2020, 14(03): 196-200.

移植后糖尿病(PTDM)是肾移植术后一种严重并发症,发病率较高。目前临床上PTDM的诊断主要根据美国糖尿病协会2018年发布的关于Ⅱ型糖尿病的诊断标准。年龄、体质指数、种族、代谢综合征、HCV血清学阳性、转录因子7类似物2基因变异、低镁血症及免疫抑制剂的应用均是肾移植术后并发PTDM的危险因素。PTDM一直是肾移植术后并发症的防治重点。了解肾移植术后并发PTDM的危险因素、监测及治疗,有助于降低PTDM发病率并提高受者生存质量。本文就近年来肾移植术后PTDM的发病风险及管理作一综述。

Post transplantation diabetes mellitus (PTDM) is a serious metabolic complication after renal transplantation. Currently, PTDM is diagnosed according to the diagnostic criteria of type Ⅱ diabetes mellitus published by American Diabetes Association in 2018. Age, body mass index, race, metabolic syndrome, HCV serologically positive, TCF7L2 genovariation, hypomagnesemia, and the use of immunosuppressive agents all affect the occurrence of PTDM in renal transplantation recipients. The PTDM in renal transplantation recipients has always been the focus of prevention and treatment of postoperative complications. Mastering the risk factors of PTDM and the management of PTDM can help reduce the incidence of PTDM and improve the quality of life of recipients. This paper reviews the possible risk factors and management methods of PTDM.

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