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中华移植杂志(电子版) ›› 2020, Vol. 14 ›› Issue (01) : 44 -48. doi: 10.3877/cma.j.issn.1674-3903.2020.01.012

所属专题: 文献

综述

肝移植术后并发急性肾损伤的诊疗进展
邓攀1, 赵于军1, 王强1, 张盛1, 明英姿1,()   
  1. 1. 410000 长沙,中南大学湘雅三医院器官移植中心
  • 收稿日期:2019-06-06 出版日期:2020-02-25
  • 通信作者: 明英姿
  • 基金资助:
    国家自然科学基金(81771722, 81700658)

Progress of diagnosis and treatment of acute kidney injury after liver transplantation

Pan Deng1, Yujun Zhao1, Qiang Wang1, Sheng Zhang1, Yingzi Ming1,()   

  1. 1. Organ Transplantation Center, Third Xiangya Hospital, Central South University, Changsha 410000, China
  • Received:2019-06-06 Published:2020-02-25
  • Corresponding author: Yingzi Ming
  • About author:
    Corresponding author: Ming Yingzi, Email:
引用本文:

邓攀, 赵于军, 王强, 张盛, 明英姿. 肝移植术后并发急性肾损伤的诊疗进展[J]. 中华移植杂志(电子版), 2020, 14(01): 44-48.

Pan Deng, Yujun Zhao, Qiang Wang, Sheng Zhang, Yingzi Ming. Progress of diagnosis and treatment of acute kidney injury after liver transplantation[J]. Chinese Journal of Transplantation(Electronic Edition), 2020, 14(01): 44-48.

肝移植是目前治疗终末期肝病的主要手段,但移植术后常并发急性肾损伤(AKI),直接或间接影响受者移植术后生存质量及长期生存率。肝移植术后并发AKI的发病机制和病理改变复杂多样。移植术前、术中和术后等多种因素(包括供、受者因素、手术和移植后早期免疫抑制剂的使用等)均可能导致AKI。本文对近年来肝移植术后并发AKI的相关研究进行综述,总结其发病机制及临床诊治经验,以期为临床预防及早期诊治提供依据,改善受者预后。

Liver transplantation is currently the main method for treating end-stage liver disease, but acute kidney injury (AKI) often occurs after transplantation, which directly or indirectly affects the recipient′s quality of life and long-term survival after transplantation. The pathogenesis and pathologic changes of AKI after liver transplantation are complex and diverse. A variety of factors (including donor and recipient factors, the use of surgery and early immunosuppressive agents after transplantation and so on) may cause AKI before, during, and after transplantation. This article tries to review the research progress on liver transplantation recipients accompanied with AKI after transplantation. The pathogenesis, and clinical diagnosis and treatment experience for AKI after liver transplantation are summarized, with a view to providing a basis for clinical prevention and early diagnosis and treatment, and improving the prognosis of the recipients.

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