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中华移植杂志(电子版) ›› 2022, Vol. 16 ›› Issue (05) : 299 -301. doi: 10.3877/cma.j.issn.1674-3903.2022.05.006

经验交流

心脏移植术后人类微小病毒B19感染致纯红细胞再生障碍性贫血三例并文献复习
陈善良1, 赵霜梅2, 许莉1, 厉泉1, 苗强1, 李敏1, 李红昕1, 刘天起1,()   
  1. 1. 250014 济南,山东第一医科大学第一附属医院(山东省千佛山医院)心血管外科 山东省心脏移植与材料工程技术研究中心
    2. 250022 济南市第五人民医院重症医学科
  • 收稿日期:2022-08-31 出版日期:2022-10-25
  • 通信作者: 刘天起
  • 基金资助:
    山东省自然科学基金(ZR2013HM028)

Pure red cell aplasia due to human parvovirus B19 infection after heart transplantation: three case reports and literature review

Shanliang Chen1, Shuangmei Zhao2, Li Xu1, Quan Li1, Qiang Miao1, Min Li1, Hongxin Li1, Tianqi Liu1,()   

  1. 1. Department of Cardiovascular Surgery, the First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering Research Center for Health Transplant and Material, Jinan 250014, China
    2. Department of Critical Care Medicine, the Fifth People′s Hospital of Jinan, Jinan 250022, China
  • Received:2022-08-31 Published:2022-10-25
  • Corresponding author: Tianqi Liu
引用本文:

陈善良, 赵霜梅, 许莉, 厉泉, 苗强, 李敏, 李红昕, 刘天起. 心脏移植术后人类微小病毒B19感染致纯红细胞再生障碍性贫血三例并文献复习[J]. 中华移植杂志(电子版), 2022, 16(05): 299-301.

Shanliang Chen, Shuangmei Zhao, Li Xu, Quan Li, Qiang Miao, Min Li, Hongxin Li, Tianqi Liu. Pure red cell aplasia due to human parvovirus B19 infection after heart transplantation: three case reports and literature review[J]. Chinese Journal of Transplantation(Electronic Edition), 2022, 16(05): 299-301.

纯红细胞再生障碍性贫血(pure red cell aplasia,PRCA)是器官移植术后以急性骨髓造血衰竭为特征的一种严重并发症,人类微小病毒B19(human parvovirus B19,HPV B19)感染是实体器官移植术后常见造成PRCA的病因。目前,各类实体器官移植术后均有HPV B19感染的报道,尤其肾移植术后较多,但多以个案报道为主[1]。心脏移植术后HPV B19感染致PRCA在国内未见报道,相关诊断及治疗尚无统一标准,在临床诊疗过程中容易造成误诊、漏诊及治疗不当。本文回顾性分析2018年10月至2020年10月山东第一医科大学第一附属医院3例心脏移植术后HPV B19感染致PRCA的受者临床资料,并通过文献复习总结此类疾病的流行病学、临床特点、诊断及治疗方法,现报道如下。

1
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