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中华移植杂志(电子版) ›› 2024, Vol. 18 ›› Issue (05) : 298 -301. doi: 10.3877/cma.j.issn.1674-3903.2024.05.008

所属专题: 经典病例

病例报告

靶向联合治疗双肺移植术后KRAS和BRAF基因双突变晚期肺腺癌一例
黄莹1, 李璇1, 刘梦杨1, 彭桂林1, 徐鑫1, 韦兵1, 杨超1,()   
  1. 1.510120 广州,广州医科大学附属第一医院胸外科
  • 收稿日期:2024-09-14 出版日期:2024-10-25
  • 通信作者: 杨超
  • 基金资助:
    国家重点研发计划(2021YFC2500900)

Targeted combination therapy for advanced lung adenocarcinoma with double mutation of KRAS and BRAF genes after double lung transplantation:a case report

Ying Huang1, Xuan Li1, Mengyang Liu1, Guilin Peng1, Xin Xu1, Bing Wei1, Chao Yang1,()   

  1. 1.Department of Thoracic Surgery, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510120, China
  • Received:2024-09-14 Published:2024-10-25
  • Corresponding author: Chao Yang
引用本文:

黄莹, 李璇, 刘梦杨, 彭桂林, 徐鑫, 韦兵, 杨超. 靶向联合治疗双肺移植术后KRAS和BRAF基因双突变晚期肺腺癌一例[J/OL]. 中华移植杂志(电子版), 2024, 18(05): 298-301.

Ying Huang, Xuan Li, Mengyang Liu, Guilin Peng, Xin Xu, Bing Wei, Chao Yang. Targeted combination therapy for advanced lung adenocarcinoma with double mutation of KRAS and BRAF genes after double lung transplantation:a case report[J/OL]. Chinese Journal of Transplantation(Electronic Edition), 2024, 18(05): 298-301.

图1 双肺移植术后KRAS和BRAF基因双突变晚期肺腺癌患者靶向联合治疗前后胸部CT图像 注:a.双肺移植术后10个月; b.接受靶向联合治疗前; c.治疗后3个月; d.治疗后16个月,主要病灶呈缩小状态; 箭头所示为主要病灶
图2 双肺移植术后KRAS和BRAF基因双突变晚期肺腺癌患者靶向联合治疗前后PET-CT图像 注:PET-CT.正电子发射计算机断层显像; a.接受靶向联合治疗前; b.治疗后10个月; 箭头所示为主要病灶
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