器官捐献档案是记录器官捐献全过程的关键资料，直接关系到捐献者与受者相关权益。随着我国器官捐献与移植事业稳步发展，需要构建科学、规范的捐献者档案管理策略。本文基于单中心实践经验，以文件生命周期理论为指导，探讨器官捐献档案全过程管理的策略与实践路径，旨在提升档案的完整性、规范性与可追溯性，以期为相关机构优化档案管理提供参考与借鉴。

Organ donation file is the key information of the whole process of organ donation, which is of vital importance to protect the rights and interests of donors and recipients. With the rapid development of organ donation and transplantation in China, the establishment of a scientific and standardized organ donation file management and quality control system has become particularly urgent. Based on the experience of a single center, this study explores the strategy and practice of the whole process management of organ donation files, guided by the Life Cyde Theory of Records, aiming to improve the quality of organ donation files and provide a referenceable experience for the management of organ donation files nationwide.