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中华移植杂志(电子版) ›› 2026, Vol. 20 ›› Issue (03) : 193 -196. doi: 10.3877/cma.j.issn.1674-3903.2026.03.007

经验交流

肝移植治疗妊娠期肝衰竭二例并文献分析
林罗娇娅, 谢仕龙, 陈滢, 张微, 卢芳燕()   
  1. 310003 杭州,浙江大学医学院附属第一医院肝移植中心
  • 收稿日期:2026-05-20 出版日期:2026-06-25
  • 通信作者: 卢芳燕
  • 基金资助:
    2025年度浙大一院护理学科建设科研项目(ZD-ZYHL-2504)

Liver transplantation for liver failure in pregnancy: two case reports and literature review

Luojiaoya Lin, Shilong Xie, Ying Chen, Wei Zhang, Fangyan Lu()   

  1. Liver Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
  • Received:2026-05-20 Published:2026-06-25
  • Corresponding author: Fangyan Lu
引用本文:

林罗娇娅, 谢仕龙, 陈滢, 张微, 卢芳燕. 肝移植治疗妊娠期肝衰竭二例并文献分析[J/OL]. 中华移植杂志(电子版), 2026, 20(03): 193-196.

Luojiaoya Lin, Shilong Xie, Ying Chen, Wei Zhang, Fangyan Lu. Liver transplantation for liver failure in pregnancy: two case reports and literature review[J/OL]. Chinese Journal of Transplantation(Electronic Edition), 2026, 20(03): 193-196.

表1 妊娠期肝衰竭病例1肝移植前后实验室指标变化趋势
表2 妊娠期肝衰竭病例2肝移植前后实验室指标变化趋势
1
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2
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3
Jalil S, Elfeki MA, Kiefer MK, et al. Waitlist and posttransplant outcomes of pregnancy-related acute liver failure in the United States[J]. Liver Transpl, 202430(6):573-581.
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唐晖,傅斌生,易慧敏,等. 肝移植治疗妊娠期合并急性肝衰竭2例并文献复习[J]. 器官移植2015, 6(3):388-391.
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Ichai P, Bouchghoul H, Laurent-Bellue A, et al. Urgent liver transplantation for acute liver failure in pregnant women: the optimum timing for delivery[J]. Transplantation, 2023107(1):172-180.
6
Alexander V, Benjamin SJ, Subramani K, et al. Acute liver failure in pregnancy[J]. Indian J Gastroenterol, 202443(2):325-337.
7
Wasuwanich P, Wen TS, Egerman RS, et al. Epidemiology and outcomes of hepatitis E virus-associated hospitalisations in the United States with a focus on pregnancy: a nationwide population study, 1998-2020[J]. J Viral Hepat, 202431(11):710-719.
8
Lao TT. Drug-induced liver injury in pregnancy[J]. Best Pract Res Clin Obstet Gynaecol, 202068:32-43.
9
鞠宇豪,李文,王雨,等. 41例慢性HBV感染危重孕产妇的临床特征分析[J]. 临床肝胆病杂志202440(2):258-263.
10
Li L, Fan M, Zhou M, et al. Early plasma exchange and continuous renal replacement therapy improve puerperal prognosis in hepatitis B virus-related acute-on-chronic liver failure in pregnancy[J]. Liver Res, 20248(2):118-126.
11
Viral Hepatitis in Pregnancy: ACOG Clinical Practice Guideline No. 6[J]. Obstet Gynecol, 2023142(3):745-759.
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Sithamparapillai K, Zachariah U, Eapen CE, et al. Plasma exchange improves survival in acute liver failure - an updated systematic review and meta-analysis focussed on comparing within single etiology[J]. Indian J Gastroenterol, 202443(2):397-406.
13
Bose R, Mohan AK, Prasanth V, et al. Management of acute liver failure during pregnancy by therapeutic plasma exchange- a multidisciplinary approach[J]. Asian J Transfus Sci, 202519(1):158-162.
14
Li L, Huang D, Xu J, et al. The assessment in patients with acute fatty liver of pregnancy (AFLP) treated with plasma exchange: a cohort study of 298 patients[J]. BMC Pregnancy and Childbirth, 202323(1):171.
15
Shen Y, Shi X, Zhang M, et al. Liver Transplantation for acute liver failure during pregnancy: case report and literature review[J]. Transplant Proc, 202355(8):1951-1955.
16
Matos LR, Reau NS. The spectrum of hepatic critical care during pregnancy: a clinical review[J]. Clin Obstet Gynecol, 202366(1):176-185.
17
Romano DN, Mokuolu DC, Katz DJ, et al. Orthotopic liver transplant in the pregnant recipient: a systematic review of preoperative management and maternal and fetal outcomes[J]. Clin Transplant, 202135(4): e14269.
18
Nie M, Teng WB, Wu P, et al. Fast-track anesthesia in a pregnant female patient undergoing liver transplantation: a case report[J]. BMC Anesthesiol, 202626(1):122.
19
Chen Y, Rothbard N, Wright M, et al. Orthotopic liver transplantation during pregnancy: the role of surgical technique[J]. Transplantation, 2025109(12): e718-e719.
20
王秋香,张成东,章心怡,等. 1例妊娠中期合并急性肝衰竭患者行肝移植手术的护理配合[J]. 中华护理杂志202560(12):1504-1507.
21
Valentin N, Guerrido I, Rozenshteyn F, et al. Pregnancy outcomes after liver transplantation: a systematic review and meta-analysis[J]. Am J Gastroenterol, 2021116(3):491-504.
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