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中华移植杂志(电子版) ›› 2022, Vol. 16 ›› Issue (03) : 168 -171. doi: 10.3877/cma.j.issn.1674-3903.2022.03.007

病例报告

祛铁治疗异基因造血干细胞移植术后三系植入不良一例
陈敏1, 潘田中2, 孙自敏3,()   
  1. 1. 230026 合肥,中国科学技术大学生命科学与医学部
    2. 230022 合肥,中国科学技术大学第一附属医院血液内科
    3. 230022 合肥,中国科学技术大学第一附属医院血液内科;215006 苏州大学第一附属医院国家血液系统疾病临床研究中心
  • 收稿日期:2022-04-09 出版日期:2022-06-25
  • 通信作者: 孙自敏
  • 基金资助:
    国家自然科学基金项目(81470350); 国家血液系统疾病临床研究中心移植研究基金(2020ZKPC03)

Iron removal therapy for poor implantation after allogeneic hematopoietic stem cell transplantation: a case report

min Chen1, Tianzhong Pan2, Zimin Sun3,()   

  1. 1. University of Science and Technology of China School of Clinical Medicine, Hefei 230026, China
    2. Department of Hematopathology, the First Affiliated Hospital of USTC, Hefei 230022, China
    3. Department of Hematopathology, the First Affiliated Hospital of USTC, Hefei 230022, China; National Research Center for Hematological Diseases, the First Affiliated Hospital of Soochow University, Suzhou 251006, China
  • Received:2022-04-09 Published:2022-06-25
  • Corresponding author: Zimin Sun
引用本文:

陈敏, 潘田中, 孙自敏. 祛铁治疗异基因造血干细胞移植术后三系植入不良一例[J]. 中华移植杂志(电子版), 2022, 16(03): 168-171.

min Chen, Tianzhong Pan, Zimin Sun. Iron removal therapy for poor implantation after allogeneic hematopoietic stem cell transplantation: a case report[J]. Chinese Journal of Transplantation(Electronic Edition), 2022, 16(03): 168-171.

异基因造血干细胞移植(allogeneic hematopoietic stem cell transplantation,allo-HSCT)是目前可能治愈血液系统恶性肿瘤的重要手段。植入功能不良(poor graft function,PGF)是allo-HSCT后一种严重并发症,预后极差,严重影响受者预后。目前关于PGF的发病机制尚不完全明确,且缺乏有效的治疗方法。本文回顾性分析中国科学技术大学附属第一医院1例重度再生障碍性贫血(aplastic anemia,AA)患者接受全相合外周血及骨髓allo-HSCT后出现PGF伴铁过载患者诊治经过,现报道如下。

图1 异基因造血干细胞移植受者移植后血三系变化及输血情况
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