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中华移植杂志(电子版) ›› 2025, Vol. 19 ›› Issue (05) : 362 -367. doi: 10.3877/cma.j.issn.1674-3903.2025.05.012

论著

基于Web of Science数据库的移植药学文献计量和可视化分析
吕欣鸽1,2, 张颖1,2, 周效竹1, 王震寰1, 崔向丽1,()   
  1. 1100050 北京,首都医科大学附属北京友谊医院药剂科
    2101149 北京,首都医科大学附属北京潞河医院药剂科
  • 收稿日期:2024-10-31 出版日期:2025-10-25
  • 通信作者: 崔向丽
  • 基金资助:
    国家卫生健康委医院药学高质量发展研究项目(NIHAYS2302); 北京慢性病防治与健康教育研究会2024年药学类专项课题(MBZX082024001)

Bibliometrics and visualization analysis of transplant pharmacy based on Web of Science database

Xinge Lv1,2, Ying Zhang1,2, Xiaozhu Zhou1, Zhenhuan Wang1, Xiangli Cui1,()   

  1. 1Department of Pharmacy, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
    2Department of Pharmacy, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China
  • Received:2024-10-31 Published:2025-10-25
  • Corresponding author: Xiangli Cui
引用本文:

吕欣鸽, 张颖, 周效竹, 王震寰, 崔向丽. 基于Web of Science数据库的移植药学文献计量和可视化分析[J/OL]. 中华移植杂志(电子版), 2025, 19(05): 362-367.

Xinge Lv, Ying Zhang, Xiaozhu Zhou, Zhenhuan Wang, Xiangli Cui. Bibliometrics and visualization analysis of transplant pharmacy based on Web of Science database[J/OL]. Chinese Journal of Transplantation(Electronic Edition), 2025, 19(05): 362-367.

目的

对移植药学领域相关文献进行文献计量和可视化分析,为国内发展移植药师队伍、开展移植药学研究和提高移植药学服务水平提供参考。

方法

检索Web of Science核心合集数据库中移植和药学相关文献,检索时间为建库至2024年12月,分析年发文量、被引频次以及发文国家、作者与机构,用CiteSpace软件检测引文突现,VOSviewer作关键词聚类分析,分析研究现状和热点。

结果

共纳入文献3 168篇,最早发表于1992年,2022年发文量最高,达273篇;总被引频次为66 740次,2024年最高,达6 116次。美国是发文量最多的国家(1 659篇),且与其他国家合作关系最密切。共3 077个机构参与发表,发文量第一的机构为美国宾夕法尼亚联邦高等教育系统(176篇)。共16 408位作者参与发表,发文量最多的作者为美国学者Taber DJ(78篇)。强度排名前十的突现引文突现持续时间为3~4年,西班牙学者Brunet M 2019年发表的《他克莫司个体化治疗药物监测第二次共识报告》是强度最高的突现引文,引文强度为37.78。60个关键词纳入聚类分析,形成3个聚类,分别聚焦在器官移植治疗效果评估、器官移植免疫治疗以及免疫抑制剂药物代谢和基因组学3个方面。

结论

通过对移植药学领域研究的可视化分析,为我国未来进一步发展器官移植药学,完善药学服务体系,开展相关研究提供方向。

Objective

Bibliometric and visualization analyses of the literature in the field of transplant pharmacy were conducted to inform the development of transplant pharmacist teams, advance transplant pharmacy research, and enhance transplant pharmacy service standards in China.

Methods

Publications related to transplantation and pharmacy were searched in the Web of Science Core Collection database from the establishment of the database to December 2024. Bibliometric method was used to analyze the annual publication output, citation frequency, as well as the countries, authors, and institutions. CiteSpace software and VOSviewer were used to detect bursts and clusters of keywords and citations, in order to analyze the current status and hotspots of the field.

Results

A total of 3 168 articles were included in this study, with the earliest publication dating back to 1992. The highest number of publications occurred in 2022 (n=273). The total number of citations was 66, 740, with the highest figure in 2024 reaching 6 116. The United States had the most publications (n=1 659) and maintained the strongest collaborations with other countries. A total of 3 077 institutions participated in the publications, with the Pennsylvania Commonwealth System of Higher Education (n=176) ranking first in publication volume. A total of 16 408 authors contributed to the publications, with Taber DJ (n=78) being the most prolific author. The top ten most intense emergent citations sustained their pre-eminence for a period of 3 to 4 years. The most significant emergent citation was "Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report" by Spanish scholar Brunet M in 2019, with a citation intensity of 37.78. Sixty keywords were subjected to cluster analysis, forming three distinct clusters. These clusters focus on three key areas: assessment of therapeutic efficacy in organ transplantation, immunotherapy in organ transplantation, and the pharmacokinetics and genomics of immunosuppressive agents.

Conclusions

By visualizing and analyzing the research in the field of transplant pharmacy, this study provides guidance for the further development of transplant pharmacy, the improvement of pharmacy services, and the conduct of related research in China in the future.

图1 1992至2024年移植药学相关文献年发文量及总被引频次
表1 1992至2024年移植药学相关文献发文量排名前十的国家及被引频次
表2 1992至2024年移植药学相关文献发文量排名前十的机构及被引频次
表3 1992至2024年移植药学相关文献发文量排名前十的作者及其论文被引频次
表4 1992至2024年移植药学相关文献强度排名前十的突现引文
引文 年份 强度 起始年份 结束年份 1992至2024突现情况
Therapeutic drug monitoring of tacrolimus-personalized therapy: second consensus report[7] 2019 37.78 2020 2024
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for CYP3A5 genotype and tacrolimus dosing[8] 2015 15.51 2016 2020
The third international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation[9] 2018 15.38 2019 2024
Cytomegalovirus in solid organ transplant recipients-Guidelines of the American Society of Transplantation Infectious Diseases Community of Practice[10] 2019 15.31 2021 2024
Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference[11] 2009 13.14 2011 2014
Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I[12] 2010 11.44 2011 2015
A randomized controlled trial comparing the efficacy of Cyp3a5 genotype-based with body-weight-based tacrolimus dosing after living donor kidney transplantation[13] 2016 10.8 2018 2021
Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients[14] 2004 10.58 2005 2009
The role of pharmacogenetics in the disposition of and response to tacrolimus in solid organ transplantation[15] 2014 10.42 2015 2019
Clinical pharmacokinetics and pharmacodynamics of mycophenolate in solid organ transplant recipients[16] 2007 9.78 2008 2012
图2 1992至2024年移植药学相关文献关键词聚类图谱
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