To summarize the clinical experience of heart-lung transplantation.

The clinical data of 11 cases of heart-lung transplantation (7 for male and 4 for female ) who got transplantation in the First Affiliated Hospital of Guangzhou Medical University from September 2015 to November 2018 were retrospectively ananlysed. The mean age of 11 recipients was (32±11). The primary diseases included 3 cases of Eisenmenger′s syndrome, 4 cases of idiopathic pulmonary arterial hypertension, and one in each of complex congenital heart disease, pulmonary embolism, cardiopulmonary failure after double lung transplantation, and cardiomyopathy with chronic obstructive pulmonary disease. The selection of donor heart and lung were according to the criteria of lung and heart transplantation. Median sternotomy were used in all cases. Cardiopulmonary bypass was established by aortic, distal superior and inferior vena cava cannulation. Diseased heart and lung were excised before donor heart and lung implantation, and then with trachea, aorta, superior and inferior vena cava anastomosis in turn.

Of the 11 recipients, 4 recipients died within 30 days after operation, among which 2 recipients died of pleural and mediastinal hemorrhage, and 2 recipients died of cerebral complication; 3 recipients died during 30 days to 1 year after operation, the cuses of death were graft dysfunction and infection caused by rejection, and multiple organ failure caused by graft dysfunction. The remaining 4 recipients were still alive during 1 year after transplantation.

Strict selection of donors and recipients and complete haemostasis for postmediastinum during transplantation can reduce surgical mortality of heart-lung transplantation and improve the survival rate and time of recipients significantly.