Research progress of hypothermic oxygenated machine perfusion in kidney preservation

doi:10.3877/cma.j.issn.1674-3903.2020.04.013

Abstract

Abstract:

Kidney transplantation is the best treatment option for end-stage renal disease. In recent years, in order to alleviate the problem of donor kidneys shortage, the use of marginal donor kidneys has been increasing, which puts forward higher requirements for donor preservation. Due to its advantages of reducing ischemia reperfusion injury of marginal donors and suppressing rejection, hypothermic oxygenated machine perfusion(HOPE) has gained widely attention again. This review will focus on the progress on HOPE in kidney perservation.

Key words: Kidney transplantation, Organ preservation, Mechanical perfusion, Oxygenation

Shujun Zhou, Yanfeng Wang. Research progress of hypothermic oxygenated machine perfusion in kidney preservation[J]. Chinese Journal of Transplantation(Electronic Edition), 2020, 14(04): 251-254.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhyzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-3903.2020.04.013

https://zhyzzz.cma-cmc.com.cn/EN/Y2020/V14/I04/251

References 41

1	Chatauret N, Coudroy R, Delpech PO, et al. Mechanistic analysis of nonoxygenated hypothermic machine perfusion′s protection on warm ischemic kidney uncovers greater eNOS phosphorylation and vasodilation[J]. Am J Transplant, 2014，14(11): 2500-2514.
2	Wszola M, Kwiatkowski A, Domagala P, et al. Preservation of kidneys by machine perfusion influences gene expression and may limit ischemia/reperfusion injury[J]. Prog Transplant, 2014，24(1): 19-26.
3	Kroemer G. B709 mitochondrial control of cell death[J]. ScientificWorldJournal, 2001，1: 48.
4	Jochmans I, Hofker HS, Davies L, et al. Oxygenated hypothermic machine perfusion of kidneys donated after circulatory death: an international randomised controlled trial[C]//26th Annual meeting of Belgian Transplantation Society, Antwerp, 2019.
5	Kron P, Schlegel A, Muller X, et al. Hypothermic oxygenated perfusion: a simple and effective method to modulate the immune response in kidney transplantation[J]. Transplantation, 2019，103(5): e128-e136.
6	Hoyer DP, Gallinat A, Swoboda S, et al. Influence of oxygen concentration during hypothermic machine perfusion on porcine kidneys from donation after circulatory death[J]. Transplantation, 2014，98(9): 944-950.
7	Pegg DE, Foreman J, Hunt CJ, et al. The mechanism of action of retrograde oxygen persufflation in renal preservation[J]. Transplantation, 1989，48(2): 210-217.
8	Kron P, Schlegel A, de Rougemont O, et al. Short, cool, and well oxygenated - HOPE for kidney transplantation in a rodent model[J]. Ann Surg, 2016，264(5): 815-822.
9	Darius T, Gianello P, Vergauwen M, et al. The effect on early renal function of various dynamic preservation strategies in a preclinical pig ischemia-reperfusion autotransplant model[J]. Am J Transplant, 2018，19(3): 752-762.
10	Thuillier R, Allain G, Celhay O, et al. Benefits of active oxygenation during hypothermic machine perfusion of kidneys in a preclinical model of deceased after cardiac death donors[J]. J Surg Res, 2013，184(2): 1174-1181.
11	Schlegel A, Kron P, Graf R, et al. Hypothermic oxygenated perfusion (HOPE) downregulates the immune response in a rat model of liver transplantation[J]. Ann Surg, 2014，260(5): 931-937.
12	Casiraghi F, Azzollini N, Todeschini M, et al. Complement alternative pathway deficiency in recipients protects kidney allograft from ischemia/reperfusion injury and alloreactive T cell response[J]. Am J Transplant, 2017，17(9): 2312-2325.
13	Mills EL, Kelly B, O′Neill LAJ. Mitochondria are the powerhouses of immunity[J]. Nat Immunol, 2017，18(5): 488-498.
14	Gallinat A, Paul A, Efferz P, et al. Role of oxygenation in hypothermic machine perfusion of kidneys from heart beating donors[J]. Transplantation, 2012，94(8): 809-813.
15	Venema LH, Brat A, Moers C, et al. Effects of oxygen during long-term hypothermic machine perfusion in a porcine model of kidney donation after circulatory death[J]. Transplantation, 2019，103(10): 2057-2064.
16	Rudolf LE, Mandel S. Supercooling, intermittent perfusion, and high pressure oxygen in whole organ preservation[J]. Transplantation, 1967，5(4): 1159-1166.
17	Edwards ML. Hyperbaric oxygen therapy. Part 1: history and principles[J]. J Vet Emerg Crit Care (San Antonio), 2010，20(3): 284-288.
18	Treckmann J, Nagelschmidt M, Minor T, et al. Function and quality of kidneys after cold storage, machine perfusion, or retrograde oxygen persufflation: results from a porcine autotransplantation model[J]. Cryobiology, 2009，59(1): 19-23.
19	Molácáček J, Opatrný V, Matějka R, et al. Retrograde oxygen persufflation of kidney - experiment on an animal[J]. In Vivo, 2016，30(6): 801-805.
20	Edwards ML. Hyperbaric oxygen therapy. Part 2: application in disease[J]. J Vet Emerg Crit Care (San Antonio), 2010，20(3): 289-297.
21	Patel K, Smith TB, Neil DAH, et al. The effects of oxygenation on ex vivo kidneys undergoing hypothermic machine perfusion[J]. Transplantation, 2019，103(2): 314-322.
22	Darius T, Vergauwen M, Smith TB, et al. Influence of different partial pressures of oxygen during continuous hypothermic machine perfusion in a pig kidney ischemia-reperfusion autotransplant model[J]. Transplantation, 2020，104(4): 731-743.
23	Ijichi H, Taketomi A, Soejima Y, et al. Effect of hyperbaric oxygen on cold storage of the liver in rats[J]. Liver Int, 2006，26(2): 248-253.
24	Guimarães FA, Taha MO, Simões MJ, et al. Apoptosis and nuclear proliferation in rat small bowel submitted to hypothermic hyperbaric oxygenation for preservation[J]. Transplant Proc, 2006，38(6): 1876-1878.
25	Amberson WR. Clinical experience with hemoglobin-saline solutions[J]. Science, 1947，106(2745): 117.
26	Brandhorst H, Asif S, Andersson K, et al. A new oxygen carrier for improved long-term storage of human pancreata before islet isolation[J]. Transplantation, 2010，89(2): 155-160.
27	Hosgood SA, Nicholson ML. The role of perfluorocarbon in organ preservation[J]. Transplantation, 2010，89(10): 1169-1175.
28	Marada T, Zacharovova K, Saudek F. Perfluorocarbon improves post-transplant survival and early kidney function following prolonged cold ischemia[J]. Eur Surg Res, 2010，44(3-4): 170-178.
29	Maluf DG, Mas VR, Yanek K, et al. Molecular markers in stored kidneys using perfluorocarbon-based preservation solution: preliminary results[J]. Transplant Proc, 2006，38(5): 1243-1246.
30	Hosgood SA, Mohamed IH, Nicholson ML. The two layer method does not improve the preservation of porcine kidneys[J]. Med Sci Monit, 2011，17(1): BR27-BR33.
31	Jahr JS, Guinn NR, Lowery DR, et al. Blood substitutes and oxygen therapeutics: a review[J]. Anesth Analg, 2019. [Ahead of print]
32	Vogel T, Brockmann JG, Coussios C, et al. The role of normothermic extracorporeal perfusion in minimizing ischemia reperfusion injury[J]. Transplant Rev (Orlando), 2012，26(2): 156-162.
33	Matton APM, Burlage LC, van Rijn R, et al. Normothermic machine perfusion of donor livers without the need for human blood products[J]. Liver Transpl, 2018，24(4): 528-538.
34	Laing RW, Bhogal RH, Wallace L, et al. The use of an acellular oxygen carrier in a human liver model of normothermic machine perfusion[J]. Transplantation, 2017，101(11): 2746-2756.
35	Mahboub P, Aburawi M, Karimian N, et al. The efficacy of HBOC-201 in ex situ gradual rewarming kidney perfusion in a rat model[J]. Artif Organs, 2020，44(1): 81-90.
36	Shonaka T, Matsuno N, Obara H, et al. Application of perfusate with human-derived oxygen carrier solution under subnormothermic machine perfusion for donation after cardiac death liver grafts in pigs[J]. Transplant Proc, 2018，50(9): 2821-2825.
37	Rousselot M, Delpy E, Drieu La Rochelle C, et al. Arenicola marina extracellular hemoglobin: a new promising blood substitute[J]. Biotechnol J, 2006，1(3): 333-345.
38	Le Gall T, Polard V, Rousselot M, et al. In vivo biodistribution and oxygenation potential of a new generation of oxygen carrier[J]. J Biotechnol, 2014，187: 1-9.
39	Tsai AG, Intaglietta M, Sakai H, et al. Microcirculation and NO-CO studies of a natural extracellular hemoglobin developed for an oxygen therapeutic carrier[J]. Curr Drug Discov Technol, 2012，9(3): 166-172.
40	Thuillier R, Dutheil D, Trieu MT, et al. Supplementation with a new therapeutic oxygen carrier reduces chronic fibrosis and organ dysfunction in kidney static preservation[J]. Am J Transplant, 2011，11(9): 1845-1860.
41	Kasil A, Giraud S, Couturier P, et al. Individual and combined impact of oxygen and oxygen transporter supplementation during kidney machine preservation in a porcine preclinical kidney transplantation model[J]. Int J Mol Sci, 2019，20(8): 1992.

[1]	Hongfeng Zhao, Shuying Wang, Wei Hu, Shijiao Nie, Ying Fei, Shangshi Shi, Huaying Chu, Jianrong Wang. Risk factors and prediction model for bloodstream infection in patients treated with extracorporeal membrane oxygenation [J]. Chinese Journal of Critical Care Medicine(Electronic Edition), 2023, 16(02): 98-104.
[2]	Jing Chen, Yang Yao, Jirong Miao, Ge Ding, Qing Ma, Yimeng Peng, Zhou Lu, Fenger Kang, Shengyu Wang. Effect of veno-arterial extracorporeal membrane oxygenation combined with intra-aortic balloon pumping on mortality in patients with cardiogenic diseases: a meta-analysis [J]. Chinese Journal of Critical Care Medicine(Electronic Edition), 2023, 16(01): 48-59.
[3]	Jiao Chen, Liwei Wang, Bin Sun, Meng Zhang, Qian Liu, Meiyan Zhou, Wenping Ding, Wei Zhang. Application of extracorporeal membrane oxygenation combined with intra-aortic balloon pumping in the treatment of fulminant myocarditis [J]. Chinese Journal of Critical Care Medicine(Electronic Edition), 2023, 16(01): 6-12.
[4]	Branch of Organ Transplant of Chinese Medical Association, Branch of Organ Transplant Physicians of Chinese Medical Doctor Association, Shanghai Pharmaceutical Profession Association. Expert Consensus on the Use of Mycophenolic Acid in Chinese Liver and Kidney Transplant Recipients (2023 edition) [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(05): 257-272.
[5]	Ruochen Qi, Shuaijun Ma, Shichao Han, Guohui Wang, Kepu Liu, Xiaoyan Zhang, Xiaojian Yang, Weijun Qin. Diagnosis and treatment of COVID-19 in kidney transplant recipients: experience from a single center [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(04): 232-239.
[6]	Weifang Zhu, Lin Chen, Jianjun Qiao. Laser combined with photodynamic therapy in the treatment of bowenoid papulosis after kidney transplantation recipient: a case report [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(04): 250-252.
[7]	Qi Chen, Jiayu Guo, Zhongbao Chen, Xiaoxiong Ma, Tianyu Wang, Jilin Zou, Long Zhang, Zhitao Cai, Tao Qiu, Jiangqiao Zhou. Combined heart and kidney transplantation: a report of 3 cases [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(02): 124-127.
[8]	Xiuyuan Zhang, Junhao Lyu, Dajin Chen. Research progress of kidney transplantation in 2022 [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(01): 32-35.
[9]	Chenchen Zhu, Fei Han, Zhangfei Shou. Kidney transplantation from HCV-positive donors: a single-center experience [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(01): 47-53.
[10]	Na Li, Dan Wang. Progress in research on hepatitis C virus infection in kidney transplant recipients [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(01): 58-62.
[11]	Min Zou, Ming Xu, Weiqiang Wu, Mingbin Gui, Feng Gao. Focus of neoadjuvant radiotherapy and chemotherapy for low rectal cancer [J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2023, 12(05): 363-371.
[12]	Ke Fang, Huanhuan Da, Jun Wang, Ruixiang Sun, Tao Wang, Yang Li, Haijiao Jiang, Weihua Lu. ECMO assisted adrenal excision for pheochromocytoma catecholamine cardiomyopathy during pregnancy: a case report and literature review [J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2023, 09(03): 304-310.
[13]	Xuehui Gao, Xiaojing Zou, Xiaobo Yang, You Shang. Anticoagulation application of Nafamostat Mesylate in critically ill patients received continuous renal replacement therapy and extracorporeal membrane oxygenation [J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2023, 09(02): 210-216.
[14]	Chengfen Yin, Lei Xu. Talk about the timing of prone position ventilation again [J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2023, 09(01): 9-13.
[15]	Cheng Qiu, Shuai Dai, Lexi Zhang, Hongtao Liu. Effect of initial blood group antibody titer on renal function and immune function in ABO blood type-incompatible live renal transplant receptors [J]. Chinese Journal of Clinicians(Electronic Edition), 2022, 16(10): 1005-1011.

Please choose a citation manager

Content to export