To investigate the effect of air pressure therapeutic apparatus in the prevention of deep vein thrombosis (DVT) of lower extremity during laparoscopic living donor hepatectomy (LLDH).

The clinical data of donors with LLDH in the Beijing Friendship Hospital from May to December 2021 were retrospectively analyzed. From May to August, 25 patients receiving routine intraoperative nursing were included in the control group. From September to December, 25 patients receiving air pressure therapeutic apparatus on the basis of routine intraoperative nursing were enrolled in the observation group. Age, sex, body mass index (BMI), length of hospital stay, incidence of DVT in lower limbs after LLDH, serum D-dimer, fibrin degradation product (FDP), prothrombin activity (PTA), activated partial thromboplastin time (APTT), antithrombin (AT)-Ⅲ, prothrombin time (PT), international normalized ratio (INR), fibrinogen (Fbg), and platelet levels on day 1 after LLDH were observed and compared between the two groups. The normal distribution measurement data were compared by group t test. Counting data were compared by Chi-square test. P<0.05 was considered statistically significant.

The incidence of postoperative DVT was 8.0% (2/25), 0% (0/25) in the control group and observation group, respectively (χ²=2.083, P>0.05). The D-dimer level and FDP in the observation group [(0.58±0.25) and (2.9±1.9) mg/L] were lower than those in the control group [(0.81±0.43) and (5.3±4.9) mg/L], respectively (t=2.365 and 2.316, all P<0.05). There were no significant differences in age, sex, BMI, length of hospital stay, PTA, APTT, AT-Ⅲ, PT, INR, Fbg and platelet levels on the first day after LLDH between the two groups (all P>0.05).

Intraoperative preventive use of air pressure therapy apparatus can effectively reduce the D-dimer and FDP levels, and reduce the risk of postoperative DVT of lower limbs, which has the value and significance of further promotion.