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中华移植杂志(电子版) ›› 2019, Vol. 13 ›› Issue (01) : 63 -66. doi: 10.3877/cma.j.issn.1674-3903.2019.01.015

所属专题: 文献

综述

固有淋巴细胞在移植免疫中的作用研究进展
周润叶1, 夏永祥2,()   
  1. 1. 210029 南京医科大学基础医学院
    2. 210029 南京医科大学第一附属医院肝胆中心
  • 收稿日期:2018-09-11 出版日期:2019-02-25
  • 通信作者: 夏永祥
  • 基金资助:
    国家自然科学基金面上项目(81771716,81571557); 江苏省"333高层次人才培养工程"(BRA2016515)

Advance in the role of innate lymphoid cell in transplantation immunity

Runye Zhou1, Yongxiang Xia2,()   

  1. 1. The School of Basic Medicine, Nanjing Medical University, Nanjing 210029, China
    2. Hepatobiliary Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
  • Received:2018-09-11 Published:2019-02-25
  • Corresponding author: Yongxiang Xia
  • About author:
    Corresponding author: Xia Yongxiang, Email:
引用本文:

周润叶, 夏永祥. 固有淋巴细胞在移植免疫中的作用研究进展[J]. 中华移植杂志(电子版), 2019, 13(01): 63-66.

Runye Zhou, Yongxiang Xia. Advance in the role of innate lymphoid cell in transplantation immunity[J]. Chinese Journal of Transplantation(Electronic Edition), 2019, 13(01): 63-66.

固有淋巴细胞(ILC)是移植免疫领域新的研究热点,其在移植免疫中的作用十分复杂。不同情况下,同种ILC可能产生促进免疫排斥或耐受两种完全相反的效应,不同ILC亚群的比例关系也会对移植免疫结果产生影响。此外,移植物组织驻留ILC也会影响移植免疫状态。本文回顾近年来相关研究,总结不同ILC亚群在移植免疫中的具体作用及相关机制,以期为进一步研究提供方向。

Innate lymphoid cell (ILC) is a new research focus in the field of transplantation. The role of ILC in transplantation immunity is very complex, and the same ILC may have two opposite effects, promoting rejection or promoting tolerance. The proportion of different ILC subgroups also affected the immune status of transplantation immunity. In addition, graft-resident ILC can also affect the state of transplantation immunity. In this paper, the relevant researches in recent years were reviewed, and to analyze the specific role and related mechanisms of different ILC subgroups in transplantation immunity, so as to provide direction for further research.

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