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中华移植杂志(电子版) ›› 2020, Vol. 14 ›› Issue (04) : 251 -254. doi: 10.3877/cma.j.issn.1674-3903.2020.04.013

所属专题: 文献

综述

肾脏低温携氧机械灌注研究进展
周书君1, 王彦峰1,()   
  1. 1. 430071 武汉大学中南医院移植外科 武汉大学肝胆疾病研究院
  • 收稿日期:2019-12-13 出版日期:2020-08-25
  • 通信作者: 王彦峰
  • 基金资助:
    国家自然科学基金(81570079)

Research progress of hypothermic oxygenated machine perfusion in kidney preservation

Shujun Zhou1, Yanfeng Wang1,()   

  1. 1. Department of Transplantation, Zhongnan Hospital of Wuhan University; Institute of Hepatobiliary Diseases of Wuhan University, Wuhan 430071, China
  • Received:2019-12-13 Published:2020-08-25
  • Corresponding author: Yanfeng Wang
  • About author:
    Corresponding author: Wang Yanfeng, Email:
引用本文:

周书君, 王彦峰. 肾脏低温携氧机械灌注研究进展[J]. 中华移植杂志(电子版), 2020, 14(04): 251-254.

Shujun Zhou, Yanfeng Wang. Research progress of hypothermic oxygenated machine perfusion in kidney preservation[J]. Chinese Journal of Transplantation(Electronic Edition), 2020, 14(04): 251-254.

肾移植是终末期肾病的最佳治疗方法。近年来,为缓解供器官短缺,边缘供肾在肾移植中的使用比例逐渐升高,对供肾保存提出了更高要求。肾脏低温携氧机械灌注(HOPE)技术具有减轻供肾缺血再灌注损伤和减少排斥反应发生的作用,受到研究人员和临床医师重视。本文就HOPE对供肾的作用和机制、氧合方式等研究进展以及存在的争议作一综述。

Kidney transplantation is the best treatment option for end-stage renal disease. In recent years, in order to alleviate the problem of donor kidneys shortage, the use of marginal donor kidneys has been increasing, which puts forward higher requirements for donor preservation. Due to its advantages of reducing ischemia reperfusion injury of marginal donors and suppressing rejection, hypothermic oxygenated machine perfusion(HOPE) has gained widely attention again. This review will focus on the progress on HOPE in kidney perservation.

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