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中华移植杂志(电子版) ›› 2022, Vol. 16 ›› Issue (01) : 55 -58. doi: 10.3877/cma.j.issn.1674-3903.2022.01.010

综述

肝癌肝移植桥接治疗进展
周辉年1, 李玉民1,()   
  1. 1. 730030 兰州大学第二医院普通外科
  • 收稿日期:2021-10-24 出版日期:2022-02-25
  • 通信作者: 李玉民
  • 基金资助:
    甘肃省2020年度重点人才项目(2020RCXM097); 兰州市人才创新创业项目(2018-RC-73)

Progress in bridging therapy of liver transplantation for hepatocellular carcinoma

Huinian Zhou1, Yumin Li1,()   

  1. 1. Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China
  • Received:2021-10-24 Published:2022-02-25
  • Corresponding author: Yumin Li
引用本文:

周辉年, 李玉民. 肝癌肝移植桥接治疗进展[J]. 中华移植杂志(电子版), 2022, 16(01): 55-58.

Huinian Zhou, Yumin Li. Progress in bridging therapy of liver transplantation for hepatocellular carcinoma[J]. Chinese Journal of Transplantation(Electronic Edition), 2022, 16(01): 55-58.

肝移植是肝癌患者的最佳治疗方式之一,在给患者带来长期生存获益方面具有显著优势,但供肝不足导致部分等待肝移植的患者因肝癌病情进展最终退出等待者名单。桥接治疗能够控制部分肝癌患者病情进展,降低等待移植患者退出率。目前,临床常用的桥接治疗方法包括介入治疗、消融治疗和放疗。随着新的系统治疗和综合治疗策略在中晚期肝癌的降期治疗中取得了突出成果,这些方法能否用于桥接治疗也值得进一步探讨。

Liver transplantation is one of the best treatment options and can bring long-term survival benefits for patients with hepatocellular carcinoma. However, insufficient donor livers have led to some patients being withdrawn from the transplant waiting list. Bridging therapy can control the progression of some hepatocellular carcinoma and reduce the dropout rate of patients waiting for transplantation. Currently, commonly used bridging treatments include interventional therapy, ablation therapy, and radiotherapy. As new systemic and comprehensive strategies have achieved good results in downstaging of advanced hepatocellular carcinoma, whether these methods can be used for bridging therapy also deserves further investigation.

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