The progress of liver transplantation for pancreatic neuroendocrine tumors with liver metastasis

doi:10.3877/cma.j.issn.1674-3903.2017.02.011

Abstract

Abstract:

Pancreatic neuroendocrine tumors (PNETs) are a heterogeneous group of tumors with low prevalence, while the prevalence of PNETs gradually increases in recent years. PNETs is prone to liver metastasis. Liver transplantation is adopted more and more for inoperable PNETs patients with liver metastasis because of the deep research of pathological mechanism, the improvement of surgical techniques and the use of new immunosuppressive drugs. This paper tried to review the progress of liver transplantation for PNETs with liver metastasis in the last few decades.

Key words: Liver transplantation, Pancreatic neuroendocrine tumors, Liver metastasis

Yuchen Hou, Linwei Wu, Xiaoshun He. The progress of liver transplantation for pancreatic neuroendocrine tumors with liver metastasis[J]. Chinese Journal of Transplantation(Electronic Edition), 2017, 11(02): 109-113.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhyzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-3903.2017.02.011

https://zhyzzz.cma-cmc.com.cn/EN/Y2017/V11/I02/109

References 41

1	Yao JC,Hassan M,Phan A, et al. One hundred years after'carcinoid’：epidemiology of and prognostic factors for neuroendocrine tumors in 35, 825 cases in the United States[J]. J Clin Oncol, 2008, 26(18): 3063-3072.
2	Lawrence B,Gustafsson BI,Chan A, et al. The epidemiology of gastroenteropancreatic neuroendocrine tumors[J]. Endocrinol Metab Clin North Am, 2011, 40(1): 1-18.
3	Ito T,Sasano H,Tanaka M, et al. Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan[J]. J Gastroenterol, 2010, 45(2): 234-243.
4	Modlin IM,Oberg K,Chung DC, et al. Gastroenteropancreatic neuroendocrine tumors[J]. Lancet Oncol, 2008, 9(1): 61-72.
5	Rindi G,Arnold R,Bosman FT, et al. Nomenclature and classification of neuroendocrine neoplasms of the digestive system//Bosman FT, Carneiro F, Hruban RH, et al. WHO Classification of Tumours of the Digestive System[M]. Lyon: IARC Press, 2010: 13-14.
6	Plockinger U,Wiedenmann B,de Herder WW. ENETS consensus guidelines for the standard of care in neuroendocrine tumors[J]. Neuroendocrinology, 2009, 90(2): 159-161.
7	CSCO神经内分泌肿瘤专家委员会. 中国胃肠胰神经内分泌肿瘤专家共识[J]. 临床肿瘤学杂志, 2013, 18(9): 815-832.
8	Mansour JC,Chen H. Pancreatic endocrine tumors[J]. J Surg Res, 2004, 120(1): 139-161.
9	杨军,周光文. 手术切除治疗胰腺神经内分泌肿瘤肝转移的META分析[J]. 中华内分泌外科杂志, 2013, 7(5): 418-423.
10	Gedaly R,Daily MF,Davenport D, et al. Liver transplantation for the treatment of liver metastases from neuroendocrine tumours-an analysis of the UNOS database[J]. Arch Surg, 2011, 146(8): 953-958.
11	Frilling A,Al-Nahhas A,Clift AK. Transplantation and debulking procedures for neuroendocrine tumors[J]. Front Horm Res, 2015, 44: 164-176.
12	Partelli S,Inama M,Rinke A, et al. Long-term outcomes of surgical management of pancreatic neuroendocrine tumors with synchronous liver metastases[J]. Neuroendocrinology, 2015, 102(1-2): 68-76.
13	Engelman ES,Leon-Ferre R,Naraev BG, et al. Comparison of transarterial liver-directed therapies for low-grade metastatic neuroendocrine tumors in a single institution[J]. Pancreas, 2014, 43(2): 219-225.
14	中华医学会肿瘤学分会胰腺癌学组. 胰腺神经内分泌肿瘤诊治专家共识[J]. 中华肿瘤杂志, 2014, 36(9): 717-720.
15	Raymond E,Dahan L,Raoul JL, et al. Sunitinib malate for the treatment of pancreatic neuroendocrine tumors[J]. N Engl J Med, 2011, 364(6): 501-513.
16	Yao JC,Shah MH,Ito T, et al. Everolimus for advanced pancreatic neuroendocrine tumors[J]. N Engl J Med, 2011, 364(6): 514-523.
17	Makowka L,Tzakis AG,Mazzaferro V, et a1.Transplantation of the liver for metastatic endocrine tumors of the intestine and pancreas[J]. Surg Gynecol Obstet, 1989, 168(2): 107-111.
18	Lehnert T. Liver transplantation for metastatic neuroendocrine carcinoma: an analysis of 103 patients[J]. Transplantation, 1998, 66(10): 1307-1312.
19	Rosenau J,Bahr M,von Wasielewski R, et al. Ki-67, E-cadherin, and p53 as prognostic indicators of long-term outcome after liver transplantation for metastatic neuroendocrine tumours[J]. Transplantation, 2002, 73(3): 386-394.
20	Florman S,Toure B,Kim L, et al. Liver transplantation for neuroendocrine tumors[J]. J Gastrointest Surg, 2004, 8(2): 208-212.
21	van Vilsteren FGI,Baskin-Bey ES,Nagorney DM, et al. Liver transplantation for gastroenteropancreatic neuroendocrine cancers; defining selection criteria to improve survival[J]. Liver Transpl, 2006, 12(3): 448-456.
22	Olausson M,Friman S,Herlenius G, et al. Orthotopic liver or multivisceral transplantation as treatment of metastatic neuroendocrine tumours[J]. Liver Transpl, 2007, 13(3): 327-333.
23	Frilling A,Malago M,Weber F, et al. Liver transplantation for patients with metastatic endocrine tumours: single-center experience with 15 patients[J]. Liver Transpl, 2006, 12(7): 1089-1096.
24	Mazzaferro V,Pulvirenti A,Coppa J. Neuroendocrine tumours metastatic to the liver: how to select patients for liver transplantation[J]. J Hepatol, 2007, 47(4): 460-466.
25	Mazzaferro V,Sposito C,Coppa J, et al. The Long-term benefit of liver transplantation for hepatic metastases from neuroendocrine tumors[J]. Am J Transplant, 2016, 16(10): 2892-2902.
26	Bonnacorsi-Riani E,Apestegui C,Jouret-Mourin A, et al. Liver transplantation and neuroendocrine tumors: lessons from a single centre experience and from the literature review[J]. Transplant Int, 2010, 23(7): 668-678.
27	Chen Xiaobo,Yang Jie,Xu Mingqing, et al. Liver transplantation for hepatic metastatic pancreatic insulinoma with a survival over five years[J]. Chin Med J (Engl), 2012, 125(15): 2768-2771.
28	Grat M,Remiszewski P,Smoter P, et al. Outcomes following liver transplantation for metastatic neuroendocrine tumors[J]. Transplant Proc, 2014, 46(8): 2766-2769.
29	Yankol Y,Mecit N,Kanmaz T, et al. Living donor liver transplantation: a life-saving option in emergency situations for diffuse hepatic neuroendocrine tumor metastasis[J]. Transplant Proc, 2015, 47(2): 427-430.
30	Le Treut YP,Gregoire E,Belghiti J, et al. Predictors of long-term survival after liver transplantation for metastatic endocrine tumors: an 85-case French multicentric report[J]. Am J Transplant, 2008, 8(6): 1205-1213.
31	Máthé Z,Tagkalos E,Paul A, et al. Liver Transplantation for hepatic metastases of neuroendocrine pancreatic tumors: a survival-based analysis[J]. Transplantation, 2011, 91(5): 575-582.
32	Nguyen NT,Harring TR,Goss JA, et al. Neuroendocrine liver metastases and orthotopic liver transplantation: the US experience[J]. Int J Hepatol, 2011: 742890.
33	Le Treut YP,Gregoire E,Klempnauer J, et al. Liver transplantation for neuroendocrine tumors in Europe-results and trends in patient selection: a 213-case European liver transplant registry study[J]. Ann Surg, 2013, 257(5): 807-815.
34	Sher LS,Levi DM,Wecsler JS, et al. Liver transplantation for metastatic neuroendocrine tumors: outcomes and prognostic variables[J]. J Surg Oncol, 2015, 112(2): 125-132.
35	Frilling A,Li J,Malamutmann E, et al. Treatment of liver metastases from neuroendocrine tumours in relation to the extent of hepatic disease[J]. Br J Surg, 2009, 96(2): 175-184.
36	Soreide O,Berstad T,Bakka A, et al. Surgical treatment as a principle in patients with advanced abdominal carcinoid tumours[J]. Surgery, 1992, 111(1): 48-54.
38	Fan ST,Le Treut,Mazzaferro V, et al. Liver transplantation for neuroendocrine tumour liver metastases[J]. HPB (Oxford), 2015, 17(1): 23-28.
39	Nobel YR,Goldberg DS. Variable use of model for end-stage liver disease exception points in patients with neuroendocrine tumors metastatic to the liver and its impact on patient outcomes[J]. Transplantation, 2015, 99(11): 2341-2346.
40	Pavel M,Baudin E,Couvelard A, et al. ENETS consensus guidelines for the management of patients with liver and other distant metastases from neuroendocrine neoplasms of foregut, midgut, hindgut, and unknown primary[J]. Neuroendocrinology, 2012, 95(2): 157-176.
41	Coppa J,Pulvirenti A,Schiavo M, et al. Resection versus transplantation for liver metastases from neuroendocrine tumors[J]. Transplant Proc, 2001, 33(1-2): 1537-1539.

[1]	Kunhe Li, Mengjia Kou, Liting Kuang. Risk factors and prediction model of reintubation after liver transplantation [J]. Chinese Archives of General Surgery(Electronic Edition), 2023, 17(05): 366-371.
[2]	Xu Tang, Bing Han, Wei Liu, Ruxing Chen. Analysis of risk factors for metachronous liver metastases after radical colorectal cancer surgery and construction of a predictive model [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2024, 18(01): 16-20.
[3]	Jian Chang, Feng Qiu, Yuqi Mao. Analysis of the relationship between ingestion inhibition factor-1 and liver metastasis after laparoscopic radical resection of colorectal cancer [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2023, 17(05): 502-505.
[4]	Branch of Organ Transplant of Chinese Medical Association, Branch of Organ Transplant Physicians of Chinese Medical Doctor Association, Shanghai Pharmaceutical Profession Association. Expert Consensus on the Use of Mycophenolic Acid in Chinese Liver and Kidney Transplant Recipients (2023 edition) [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(05): 257-272.
[5]	Wenqing Lu, Xinyi Chen, Xuefei Ren. Investigation on the quality of life after liver transplantation in children with genetic metabolic diseases [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(05): 287-292.
[6]	Tieyan Fan, Jun Li, Hong Chen. Diagnosis and treatment experience of new onset viral hepatitis E after liver transplantation [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(05): 293-296.
[7]	Shuo Chen, Feng Chen, Fei Cheng, Jie Xiang. Pancreas infarction after liver transplantation for glycogen storage disease type Ⅰ complicated with pancreatitis: a case report [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(05): 300-302.
[8]	Penghao Tang, Wu Zhang. Progress in mechanism research about intestinal microecology with perioperative complications of liver transplantation [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(05): 303-307.
[9]	Qing Yan, Ying Liu, Feiwen Deng, Huanwei Chen. Effect of microvascular invasion on survival and prognosis of liver transplantation recipients with liver cancer [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(06): 624-629.
[10]	Mei Liao, Hongjun Zhang, Jieyang Jin, Yan Lyu, Jie Ren. Diagnostic value of bedside contrast-enhanced ultrasound for early hepatic artery thrombosis after liver transplantation [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(06): 630-634.
[11]	Binglin Li, Shaocheng Lyu, Fei Pan, Tao Jiang, Hua Fan, Jiantao Kou, Qiang He, Ren Lang. Correlation analysis between pathogenic bacteria of donor liver perfusion fluid and early infection after liver transplantation [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(06): 656-660.
[12]	Lei Lyu, Xiao Feng, Kaiming He, Kaining Zeng, Qing Yang, Haijin Lyu, Huimin Yi, Shuhong Yi, Yang Yang, Binsheng Fu. Value of revised King's score in evaluation of live transplantation timing for children with acute liver failure due to Wilson's disease and literature review [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(06): 661-668.
[13]	Menglong Wang. Significance of biological characteristics in liver transplantation for HCC [J]. Chinese Journal of Hepatic Surgery(Electronic Edition), 2023, 12(05): 490-494.
[14]	Qi Liu, Kai Zhang, Jiannan Li, Tongjun Liu. Current status and progress of biologic treatment for colorectal cancer liver metastases [J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2023, 12(05): 415-419.
[15]	Daijiang Liu, Junyan Jiang, Xiaoqiang Wan, Shaying Ma. Analysis of survival status and prognostic factors in patients with colorectal cancer with liver metastasis [J]. Chinese Journal of Digestion and Medical Imageology(Electronic Edition), 2023, 13(05): 284-288.

Please choose a citation manager

Content to export