Research advances of statins on liver ischemic reperfusion injury

doi:10.3877/cma.j.issn.1674-3903.2018.03.010

Abstract

Abstract:

Ischemic reperfusion injury is almost unavoidable in liver resection surgery and liver transplantation, which is also one of the major risk factors of liver transplantation and affects the short-term and long-term outcome of liver transplantation recipients. Previous study found that Kruppel-like factor 2 induced by stains play an protective role in the regulation of endothelial function, such as anti-inflammation, anti-thrombosis, anti-oxidant stress, anti-apoptosis, and so on. This review summarizes the current understanding of statins on liver ischemic reperfusion injury.

Key words: Stains, Kruppel-like factor 2, Liver, Ischemia reperfusion injury

Zhongzhong Liu, Shaojun Ye, Xingjian Zhang, Yanfeng Wang, Qifa Ye. Research advances of statins on liver ischemic reperfusion injury[J]. Chinese Journal of Transplantation(Electronic Edition), 2018, 12(03): 139-142.

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URL: https://zhyzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-3903.2018.03.010

https://zhyzzz.cma-cmc.com.cn/EN/Y2018/V12/I03/139

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