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Chinese Journal of Transplantation(Electronic Edition) ›› 2020, Vol. 14 ›› Issue (03): 196-200. doi: 10.3877/cma.j.issn.1674-3903.2020.03.014

Special Issue:

• Review • Previous Articles    

Research progress and risk management of post transplantation diabetes mellitus in renal transplantation recipients

Hongmei Yu1, Zhuowen Hao1, Gongpeng Sun1, Zhipeng Fan1, Li Dong1, Qifa Ye2,()   

  1. 1. Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University & Hubei Key Laboratory of Transplant Medical technology on Transplantation, Wuhan 430071, China
    2. Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University & Hubei Key Laboratory of Transplant Medical technology on Transplantation, Wuhan 430071, China; The 3rd Xiangya Hospital of Central Sourth University & Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha 410013, China
  • Received:2020-01-21 Online:2020-06-25 Published:2020-06-25
  • Contact: Qifa Ye
  • About author:
    Corresponding author: Ye Qifa, Email:

Abstract:

Post transplantation diabetes mellitus (PTDM) is a serious metabolic complication after renal transplantation. Currently, PTDM is diagnosed according to the diagnostic criteria of type Ⅱ diabetes mellitus published by American Diabetes Association in 2018. Age, body mass index, race, metabolic syndrome, HCV serologically positive, TCF7L2 genovariation, hypomagnesemia, and the use of immunosuppressive agents all affect the occurrence of PTDM in renal transplantation recipients. The PTDM in renal transplantation recipients has always been the focus of prevention and treatment of postoperative complications. Mastering the risk factors of PTDM and the management of PTDM can help reduce the incidence of PTDM and improve the quality of life of recipients. This paper reviews the possible risk factors and management methods of PTDM.

Key words: Renal transplantation, Post transplantation diabetes mellitus, Risk factors, Risk evaluation, Immunosuppression

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