基于德尔菲法探讨在活体器官捐献过程中设置冷静期。

通过文献查阅和专家讨论，初步确定活体器官捐献冷静期定义、分类分组方法，通过邮件发放问卷，经过三轮咨询后就冷静期定义、分类分组方法达成共识，并确定冷静期时长。

活体器官捐献冷静期是指活体器官拟捐献者从获得所有关于器官捐献与器官移植的必要信息到提出活体器官捐献申请之间必须间隔的最短时间。将活体器官捐献按捐献器官分为三类：(1)肝脏捐献；(2)肺脏捐献；(3)肾脏捐献/小肠捐献/胰腺捐献。肝脏捐献根据受者终末期肝病模型评分、儿童终末期肝病评分分为高危组、中危组和低危组；≥12岁肺脏捐献根据受者肺源分配评分分为高危组、中危组和低危组，<12岁肺脏捐献根据医疗紧急程度分高危组和低危组；肾脏捐献、小肠捐献和胰腺捐献不进行分组。肝脏捐献和肺脏捐献高危组冷静期1 d、中危组冷静期7 d、低危组冷静期14 d；肾脏捐献、小肠捐献和胰腺捐献冷静期14 d。

基于三轮德尔菲法咨询，确定活体器官捐献冷静期定义、分类分组方法和时长设置。

To explore the establishment of a cooling off period in the process of living organ donation based on the Delphi method.

Through literature review and expert discussion, the definition, classification, and grouping suggestions for the cooling off period of living organ donation have been preliminarily determined. A questionnaire was distributed via email, and after three rounds of consultation, consensus was reached on the definition, classification, and grouping methods of the cooling off period, and the duration of the cooling off period was determined.

The cooling off period for living organ donation referred to the shortest time interval between obtaining all necessary information about organ donation and submitting an application for living organ donation for the intended donor. Living organ donation was divided into three categories: (1) liver donation; (2) lung donation; (3) kidney donation/small intestine donation/pancreas donation. Liver donation was divided into high-risk, medium-risk, and low-risk groups based on the model for end-stage liver disease score and pediatric end-stage liver disease score of organ recipients. Lung donation aged ≥ 12 years was divided into high-risk, medium-risk, and low-risk groups based on the lung allocation score of organ recipients, while aged<12 years was divided into high-risk and low-risk groups based on medical urgency. Kidney donation/small intestine donation/pancreas donation were not grouped. The cooling off period for high-risk liver and lung donation groups was 1 d, for medium-risk groups was 7 d, and for low-risk groups was 14 d. The cooling off period for kidney donation/small intestine donation/pancreas donation was 14 d.

Based on three rounds of Delphi method consultation, the definition, classification and grouping method, and duration setting of the cooling off period for living organ donation were determined.