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Chinese Journal of Transplantation(Electronic Edition) ›› 2017, Vol. 11 ›› Issue (01): 44-49. doi: 10.3877/cma.j.issn.1674-3903.2017.01.011

Special Issue:

• Review • Previous Articles     Next Articles

Research and treatment progress on post-transplantation diabetes mellitus caused by tacrolimus

Lu Li1, Huizhen Chen2, Xingguang Liang3, Yahong Wu3, Shenghua Yang3, Yujie Huang4, Mingzhu Huang5,()   

  1. 1. Department of Pharmacy, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
    2. Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China
    3. Central Laboratory, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
    4. Clinical Pharmacy Center, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
    5. Department of Pharmacy, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; Central Laboratory, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
  • Received:2016-09-08 Online:2017-02-25 Published:2017-02-25
  • Contact: Mingzhu Huang
  • About author:
    Corresponding author: Huang Mingzhu, Email:

Abstract:

Post-transplantation diabetes mellitus (PTDM) is one of the most common and severe complications after solid organ transplantation. PTDM is a high risk factor for graft dysfunction, infection, cardiovascular complications and acute graft rejection, which affected survival rate and the quality of life of recipients. Tacrolimus is a powerful kind of immunosuppressant which is widely used on organ recipients. However, tacrolimus is more diabetogenic than other kind of immunosuppressant. Here we summarized the research and treatment progress of tacrolimus on PTDM.

Key words: Tacrolimus, Immunosuppressant, Post-transplantation diabetes mellitus

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