Research progress of kidney transplantation in 2022

doi:10.3877/cma.j.issn.1674-3903.2023.01.004

Abstract

Abstract:

Kidney transplantation, the preferred treatment for patients with end-stage renal disease, has given millions of uremic patients a second chance in life. In the past year, as the world fought against the COVID-19, excellent outcomes had been achieved in the field of kidney transplantation in China and abroad. This article summarizes advances and achievements in the field focusing on donor sources, the influence and prevention of COVID-19 on kidney transplantation, graft rejection, immunologic tolerance, regenerative medicine in 2022.

Key words: Kidney transplantation, Rejection, Immunologic tolerance, Regenerative medicine

Xiuyuan Zhang, Junhao Lyu, Dajin Chen. Research progress of kidney transplantation in 2022[J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(01): 32-35.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhyzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-3903.2023.01.004

https://zhyzzz.cma-cmc.com.cn/EN/Y2023/V17/I01/32

References 43

1	Aubert O, Yoo D, Zielinski D, et al. COVID-19 pandemic and worldwide organ transplantation: a population-based study[J]. Lancet Public Health, 2021, 6(10): e709-e719.
2	国务院应对新型冠状病毒肺炎疫情联防联控机制综合组. 关于对新型冠状病毒感染实施"乙类乙管"的总体方案[EB/OL]. (2022-12-07)[2023-01-05]. URL
3	Peghin M, Grossi PA. COVID-19 positive donor for solid organ transplantation[J]. J Hepatol, 2022, 77(4): 1198-1204.
4	Bock MJ, Vaughn GR, Chau P, et al. Organ transplantation using COVID-19-positive deceased donors[J]. Am J Transplant, 2022, 22(9): 2203-2216.
5	Dhand A, Okumura K, Nabors C, et al. Solid organ transplantation from COVID positive donors in the United States: analysis of United Network for Organ Sharing Database[J]. Transpl Infect Dis, 2022: e13925.
6	国家卫生健康委办公厅，中央军委后勤保障部卫生局. 血站新冠病毒感染防控工作指引(第二版) [EB/OL]. (2022-12-17)[2023-01-05]. URL
7	中华医学会器官移植学分会，中国医师协会器官移植医师分会，国家人体捐献器官获取质量控制中心. 新型冠状病毒感染者器官捐献专家共识[J]. 器官移植，2023, 14(1): 1-10.
8	Brogan M, Ross MJ. COVID-19 and kidney disease[J]. Annu Rev Med, 2023, 74：1-13.
9	Pacheco ICR, Costa D, Sousa DS, et al. Kidney injury associated with COVID-19 infection and vaccine: a narrative review [J]. Front Med (Lausanne), 2022, 9: 956158.
10	Menez S, Parikh CR. COVID-19 and the kidney: recent advances and controversies[J]. Seminars in nephrology, 2022, 42(3): 151279.
11	Yang Y, Zou S, Xu G. An update on the interaction between COVID-19, vaccines, and diabetic kidney disease[J]. Front Immunol, 2022, 13: 999534.
12	Silva-Aguiar RP, Teixeira DE, Peres RaS, et al. Subclinical acute kidney injury in COVID-19: possible mechanisms and future perspectives[J]. Int J Mol Sci, 2022, 23(22): 14193.
13	Nogueira GM, Silva N, Moura AF, et al. Acute kidney injury and electrolyte disorders in COVID-19[J]. World J Virol, 2022, 11(5): 283-292.
14	Stein SR, Ramelli SC, Grazioli A, et al. SARS-CoV-2 infection and persistence in the human body and brain at autopsy[J]. Nature, 2022, 612(7941): 758-763.
15	Braun F, Lütgehetmann M, Pfefferle S, et al. SARS-CoV-2 renal tropism associates with acute kidney injury[J]. Lancet, 2020, 396(10251): 597-598.
16	Diao B, Wang C, Wang R, et al. Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection[J]. Nat Commun, 2021, 12(1): 2506.
17	Golmai P, Larsen CP, Devita MV, et al. Histopathologic and ultrastructural findings in postmortem kidney biopsy material in 12 patients with AKI and COVID-19[J]. J Am Soc Nephrol, 2020, 31(9): 1944-1947.
18	Sharma P, Uppal NN, Wanchoo R, et al. COVID-19-associated kidney injury: a case series of kidney biopsy findings[J]. J Am Soc Nephrol, 2020, 31(9): 1948-1958.
19	Wang L, Li X, Chen H, et al. Coronavirus disease 19 infection does not result in acute kidney injury: an analysis of 116 hospitalized patients from Wuhan, China[J]. Am J Nephrol, 2020, 51(5): 343-348.
20	Wang W, Xu Y, Gao R, et al. Detection of SARS-CoV-2 in different types of clinical specimens[J]. Jama, 2020, 323(18): 1843-1844.
21	林俊，丁小明，朱一辰，等. 肾移植受者新型冠状病毒疫苗接种建议[J] . 中华器官移植杂志，2022, 43(2)：67-73.
22	Li L, Chen X, Li B, et al. Effect of inactivated SARS-CoV-2 vaccine on thyroid function and autoimmunity within 28 days after the second dose [J]. Thyroid, 2022, 32(9): 1051-1058.
23	Xiong X, Wong CKH, Au ICH, et al. Safety of inactivated and mRNA COVID-19 vaccination among patients treated for hypothyroidism: a population-based cohort study[J]. Thyroid, 2022, 32(5): 505-514.
24	崔瑜，张雷，，吴建永. 肾移植抗体介导排斥反应的预防及诊疗要点[J]. 中华医学杂志，2022, 102(26)：2041-2044.
25	Ramalhete LM, Araújo R, Ferreira A, et al. Proteomics for biomarker discovery for diagnosis and prognosis of kidney transplantation rejection[J]. Proteomes, 2022, 10(3)：24.
26	Nakorchevsky A, Hewel JA, Kurian SM, et al. Molecular mechanisms of chronic kidney transplant rejection via large-scale proteogenomic analysis of tissue biopsies[J]. J Am Soc Nephrol, 2010, 21(2): 362-373.
27	Lin XC, Sui WG, Qi SW, et al. Quantitative proteomic profiling of renal tissue in human chronic rejection biopsy samples after renal transplantation[J]. Transplant Proc, 2015, 47(2): 323-331.
28	Paşatu-Cornea AM, Ciciu E, Tuţǎ LA. Perforin: an intriguing protein in allograft rejection immunology (Review) [J]. Exp Ther Med, 2022, 24(2): 519.
29	Loga L, Dican L, Matei HV, et al. Relevant biomarkers of kidney allograft rejection[J]. J Med Life, 2022, 15(11): 1330-1333.
30	Dhrolia M, Ahmad A. Development of Banff Classification from 1991 to 2019 for identifying renal allograft rejection: a narrative review for nephrologists[J]. J Pak Med Assoc, 2022, 72(8)：1615-1621.
31	Ho J, Rush DN, Krokhin O, et al. Elevated urinary matrix metalloproteinase-7 detects underlying renal allograft inflammation and injury[J]. Transplantation, 2016, 100(3): 648-654.
32	Heidari SS, Nafar M, Kalantari S, et al. Urinary epidermal growth factor is a novel biomarker for early diagnosis of antibody mediated kidney allograft rejection: a urinary proteomics analysis[J]. J Proteomics, 2021, 240: 104208.
33	Sui W, Huang L, Dai Y, et al. Proteomic profiling of renal allograft rejection in serum using magnetic bead-based sample fractionation and MALDI-TOF MS[J]. Clin Exp Med, 2010, 10(4): 259-268.
34	Yeo WS, Ng QX. Biomarkers of immune tolerance in kidney transplantation: an overview [J]. Pediatr Nephrol, 2022, 37(3): 489-498.
35	Braud C, Baeten D, Giral M, et al. Immunosuppressive drug-free operational immune tolerance in human kidney transplant recipients: Part I. Blood gene expression statistical analysis[J]. J Cell Biochem, 2008, 103(6): 1681-1692.
36	Brouard S, Mansfield E, Braud C, et al. Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance[J]. Proc Natl Acad Sci U S A, 2007, 104(39): 15448-15453.
37	Torrico S, Hotter G, Játiva S. Development of cell therapies for renal disease and regenerative medicine[J]. Int J Mol Sci, 2022, 23(24): 15943.
38	Bednar KJ, Lee JH, Ort T. Tregs in autoimmunity: Insights into intrinsic brake mechanism driving pathogenesis and immune homeostasis[J]. Front Immunol, 2022, 13: 932485.
39	Qu G, Chen J, Li Y, et al. Current status and perspectives of regulatory T cell-based therapy [J]. J Genet Genomics, 2022, 49(7): 599-611.
40	Petrosyan A, Montali F, Peloso A, et al. Regenerative medicine technologies applied to transplant medicine. An update [J]. Front Bioeng Biotechnol, 2022, 10: 1015628.
41	Matsuzaka Y, Yashiro R. Therapeutic strategy of mesenchymal-stem-cell-derived extracellular vesicles as regenerative medicine[J]. Int J Mol Sci, 2022, 23(12)：6480.
42	García-Perdomo HA, Jurado-Penagos A. Application of regenerative medicine and 3d bioprinting in urology[J]. Actas urologicas espanolas, 2022, 46(6): 323-328.
43	Bejoy J, Qian ES, Woodard LE. Tissue culture models of AKI: from tubule cells to human kidney organoids[J]. J Am Soc Nephrol, 2022, 33(3): 487-501.

[1]	Cheng Zhou, Ye Yuan, Peng Zhang, Ming Cai, Junhua Chen, Yuping Yin, Wei Li, Fan Xiang, Gang Li, Kaixiong Tao, Zheng Wang, Guobin Wang. A new era of small bowel transplantation：Both achievements and challenges [J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2022, 16(06): 703-706.
[2]	Branch of Organ Transplant of Chinese Medical Association, Branch of Organ Transplant Physicians of Chinese Medical Doctor Association, Shanghai Pharmaceutical Profession Association. Expert Consensus on the Use of Mycophenolic Acid in Chinese Liver and Kidney Transplant Recipients (2023 edition) [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(05): 257-272.
[3]	Ruochen Qi, Shuaijun Ma, Shichao Han, Guohui Wang, Kepu Liu, Xiaoyan Zhang, Xiaojian Yang, Weijun Qin. Diagnosis and treatment of COVID-19 in kidney transplant recipients: experience from a single center [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(04): 232-239.
[4]	Weifang Zhu, Lin Chen, Jianjun Qiao. Laser combined with photodynamic therapy in the treatment of bowenoid papulosis after kidney transplantation recipient: a case report [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(04): 250-252.
[5]	Ziye Ai, Ling Li, Chongxiang He, Wei Huang, Qifa Ye. Research progress on xenotransplantation form pig organs [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(03): 186-191.
[6]	Qi Chen, Jiayu Guo, Zhongbao Chen, Xiaoxiong Ma, Tianyu Wang, Jilin Zou, Long Zhang, Zhitao Cai, Tao Qiu, Jiangqiao Zhou. Combined heart and kidney transplantation: a report of 3 cases [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(02): 124-127.
[7]	Na Li, Dan Wang. Progress in research on hepatitis C virus infection in kidney transplant recipients [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(01): 58-62.
[8]	Chenchen Zhu, Fei Han, Zhangfei Shou. Kidney transplantation from HCV-positive donors: a single-center experience [J]. Chinese Journal of Transplantation(Electronic Edition), 2023, 17(01): 47-53.
[9]	Luhao Liu, Guojun Li, Yunyi Xiong, Rongxin Chen, Wei Yin, Lei Zhang, Guanghui Li, Jiali Fang, Junjie Ma, Zheng Chen. Predictive value of donor-derived cell-free DNA in simultaneous pancreas-kidney transplantation recipients with acute rejection [J]. Chinese Journal of Transplantation(Electronic Edition), 2022, 16(06): 353-358.
[10]	Wenbo Yang, Shicong Lai, Xiaopeng Zhang, Zixiong Huang, Weiyu Zhang, Jian Zhang, Rumei Bi, Tao Yu, Qiang Wang. Application of recipient internal iliac artery carrel patch in artery reconstruction during pediatric kidney transplantation: 12 cases [J]. Chinese Journal of Transplantation(Electronic Edition), 2022, 16(06): 365-368.
[11]	Hongbing Wu, Zhiwei Wang, Luocheng Li, Zongli Ren, Junxia Hu, Peng Song, Yongle Ruan. Clinical experience of combined heart and kidney transplantation in the treatment of simultaneous end-stage cardiac and renal dysfunction: two cases [J]. Chinese Journal of Transplantation(Electronic Edition), 2022, 16(06): 369-372.
[12]	Shaohua Shi, Xinglong Yue, Lijun Zhu, Xiaotong Wu. Plasma cell-rich acute rejection in transplanted kidney: a case report and literature review [J]. Chinese Journal of Transplantation(Electronic Edition), 2022, 16(06): 373-375.
[13]	Zizhen Zhao, Zijuan Yan, Jiachuan Wang. Advances in brain organoid culture technology and its application in the repair of ischemic stroke injury [J]. Chinese Journal of Cell and Stem Cell(Electronic Edition), 2023, 13(02): 121-128.
[14]	Cheng Qiu, Shuai Dai, Lexi Zhang, Hongtao Liu. Effect of initial blood group antibody titer on renal function and immune function in ABO blood type-incompatible live renal transplant receptors [J]. Chinese Journal of Clinicians(Electronic Edition), 2022, 16(10): 1005-1011.
[15]	Xiaoning Liang, Chaoyang Lv, Ruijun Guo. Application of bedside ultrasound in simultaneous pancreas-kidney transplantation for type I diabetes mellitus [J]. Chinese Journal of Clinicians(Electronic Edition), 2022, 16(06): 553-557.

Please choose a citation manager

Content to export