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Chinese Journal of Transplantation(Electronic Edition) ›› 2024, Vol. 18 ›› Issue (05): 310-314. doi: 10.3877/cma.j.issn.1674-3903.2024.05.010

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Research progress on the prognosis and treatment of hypersplenism after liver transplantation

Jian He1, Li Zhang1, Honghai Wang1, Wentao Jiang1,()   

  1. 1.Department of Liver Transplantation, Tianjin First Central Hospital, Nankai University Institute of Transplantation Medicine, Tianjin Key Laboratory of Organ Transplantation, Tianjin Key Laboratory of Molecular Diagnosis and Treatment of Liver Cancer,Tianjin 300392, China
  • Received:2024-06-13 Online:2024-10-25 Published:2025-01-13
  • Contact: Wentao Jiang

Abstract:

Hypersplenism is a common complication in cirrhotic patients with portal hypertension. The main manifestations are splenomegaly and hemocytopenia. The outcome of patients with hypersplenism after liver transplantation is different due to the severity of the disease. At the same time, the treatment methods and principles of hypersplenism are different in different stages during liver transplantation. This article reviews the status quo of hypersplenism in liver cirrhosis, the changes of hypersplenism after liver transplantation, its potential mechanism and treatment, in order to provide reference for the diagnosis and treatment of hypersplenism resulted from cirrhosis.

Key words: Hypersplenism, Liver cirrhosis, Liver transplantation

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