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中华移植杂志(电子版) ›› 2021, Vol. 15 ›› Issue (05) : 295 -297. doi: 10.3877/cma.j.issn.1674-3903.2021.05.008

病例报告

肝移植术后血管麻痹综合征一例
彭昇1, 卢中山1, 柳安雄1, 梁文进1, 钟自彪1, 叶少军1, 叶啟发2,()   
  1. 1. 430071 武汉大学中南医院 武汉大学肝胆疾病研究院 武汉大学移植医学中心 国家人体捐献器官获取质量控制中心 移植医学技术湖北省重点实验室 湖北省天然高分子生物肝临床医学研究中心 湖北省天然高分子基医用材料构建工程技术研究中心
    2. 430071 武汉大学中南医院 武汉大学肝胆疾病研究院 武汉大学移植医学中心 国家人体捐献器官获取质量控制中心 移植医学技术湖北省重点实验室 湖北省天然高分子生物肝临床医学研究中心 湖北省天然高分子基医用材料构建工程技术研究中心;410013 长沙,中南大学湘雅三医院 卫生部移植医学工程技术研究中心
  • 收稿日期:2021-03-09 出版日期:2021-10-25
  • 通信作者: 叶啟发
  • 基金资助:
    国家自然科学基金(81970548); 医学腾飞计划——"转化医学、医学+平台建设项目"(临床医学)(TFLC2018003); 武汉市科技计划项目(2019020701011485)

Vasoplegic syndromes after liver transplantation: a case report

Sheng Peng1, Zhongshan Lu1, Anxiong Liu1, Wenjin Liang1, Zibiao Zhong1, Shaojun Ye1, Qifa Ye2,()   

  1. 1. Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, National Quality Control Center for Donated Organ Procurement, Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Clinical Research Center for Natural Polymer Biological Liver, Hubei Engineering Center of Natural Polymer-based Medical Materials, Wuhan 430071, China
    2. Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, National Quality Control Center for Donated Organ Procurement, Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Clinical Research Center for Natural Polymer Biological Liver, Hubei Engineering Center of Natural Polymer-based Medical Materials, Wuhan 430071, China; The 3rd Xiangya Hospital of Central South University, Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha 410013, China
  • Received:2021-03-09 Published:2021-10-25
  • Corresponding author: Qifa Ye
引用本文:

彭昇, 卢中山, 柳安雄, 梁文进, 钟自彪, 叶少军, 叶啟发. 肝移植术后血管麻痹综合征一例[J]. 中华移植杂志(电子版), 2021, 15(05): 295-297.

Sheng Peng, Zhongshan Lu, Anxiong Liu, Wenjin Liang, Zibiao Zhong, Shaojun Ye, Qifa Ye. Vasoplegic syndromes after liver transplantation: a case report[J]. Chinese Journal of Transplantation(Electronic Edition), 2021, 15(05): 295-297.

表1 血管麻痹综合征治疗药物[14,18]
1
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2
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3
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4
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5
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6
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7
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8
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9
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10
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11
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12
Orozco VD, Triana SC, Orozco VA. Vasoplegic syndrome in cardiac surgery: Definitions, pathophysiology, diagnostic approach and management[J]. Rev Esp Anestesiol Reanim, 2019, 66(5): 277-287.
13
Shapeton AD, Mahmood F, Ortoleva JP. Hydroxocobalamin for the treatment of vasoplegia: A review of current literature and considerations for use[J]. J Cardiothorac Vasc Anesth, 2019, 33(4): 894-901.
14
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15
Bezinover D, McQuillan P, Rossignol J, et al. Vasoplegic shock during liver transplantation: is the preoperative cGMP plasma level a potential predictor of hemodynamic instability?[J]. Med Sci Monit, 201016(9): S114-S117.
16
Wagener G, Kovalevskaya G, Minhaz M, et al. Vasopressin deficiency and vasodilatory state in end-stage liver disease[J]. J Cardiothorac Vasc Anesth, 2011, 25(4): 665-670.
17
Hajjar LA, Vincent JL, Barbosa Gomes Galas FR, et al. Vasopressin versus norepinephrine in patients with vasoplegic shock after cardiac surgery: The VANCS randomized controlled trial[J]. Anesthesiology, 2017126(1): 85-93.
18
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19
石屹崴,于洪丽,张桂诚,等. 亲体肾移植术肾动脉开放后血管麻痹综合征1例[J]. 江苏医药2021, 47(8): 860-862.
20
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21
Russell JA, Vincent JL, Kjolbye AL, et al. Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients[J]. Crit Care, 2017, 21(1): 213.
22
Prakash V, Choudhury AK, Sarin SK. Early introduction of a combination of low dose terlipressin and noradrenaline as vasopressors is superior to high dose noradrenaline alone in patients of cirrhosis with septic shock[J]. Hepatology, 2017, 66: 138A.
23
Rodriguez R, Cucci M, Kane S, et al. Novel vasopressors in the treatment of vasodilatory shock: A systematic review of angiotensin II, selepressin, and terlipressin[J]. J Intensive Care Med, 2020, 35(4): 327-337.
24
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25
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