Shanxi Organ Procurement Organization (OPO) was founded as the first independent provincial OPO in China, the "Shanxi Model" provided a solution for the standardization of organ procurement in China. In 2020, a Scientific Committee was established within our OPO. Multidisciplinary experts were brought together to provide guidance on the direction of the scientific research. Various kinds of consultations were made with relevant professionals to carry out scientific research programs and formulate expert consensus. Through combining research results with clinical experience, we tried to figure out how to inspire the networks supporting organ donation and procurement. This paper explored the direction of professionalism of organ donation and the development of our OPO, providing detailed insights into talent cultivation, theoretical framework construction, international cooperation, as well as data transformation. With the aim of adhering to the principles of standardized and high-quality development of organ donation, we tried to continuously advance the scientific construction of our OPO and thereby promoted the professional development of organ donation.