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中华移植杂志(电子版)

中华移植杂志(电子版) ›› 2021, Vol. 15 ›› Issue (06) : 370 -374. doi: 10.3877/cma.j.issn.1674-3903.2021.06.009

综述

肾移植术后液体管理改善移植肾功能延迟恢复的研究进展
徐艳1, 何重香1, 周鑫1, 潘丽1, 叶啟发2,†()   
  1. 1. 430071　武汉大学中南医院　武汉大学肝胆疾病研究院　武汉大学移植医学中心　国家人体捐献器官获取质量控制中心　移植医学技术湖北省重点实验室　湖北省天然高分子生物肝临床医学研究中心　湖北省天然高分子基医用材料构建工程技术研究中心
    2. 430071　武汉大学中南医院　武汉大学肝胆疾病研究院　武汉大学移植医学中心　国家人体捐献器官获取质量控制中心　移植医学技术湖北省重点实验室　湖北省天然高分子生物肝临床医学研究中心　湖北省天然高分子基医用材料构建工程技术研究中心；410013　长沙，中南大学湘雅三医院　卫生部移植医学工程技术研究中心
  • 收稿日期:2021-04-06 出版日期:2021-12-25
  • 通信作者: 叶啟发
  • 基金资助:
    国家自然科学基金(81970548)

The progress of post-operative fluid management improves delayed graft function in kidney transplantation

Yan Xu1, Chongxiang He1, Xin Zhou1, Li Pan1, Qifa Ye2,†()   

  1. 1. Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, National Quality Control Center for Donated Organ Procurement, Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Clinical Research Center for Natural Polymer Biological Liver, Hubei Engineering Center of Natural Polymer-based Medical Materials, Wuhan 430071, China
    2. Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, National Quality Control Center for Donated Organ Procurement, Hubei Key Laboratory of Medical Technology on Transplantation, Hubei Clinical Research Center for Natural Polymer Biological Liver, Hubei Engineering Center of Natural Polymer-based Medical Materials, Wuhan 430071, China; The Third Xiangya Hospital of Central South University, Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha 410013, China
  • Received:2021-04-06 Published:2021-12-25
  • Corresponding author: Qifa Ye
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引用本文：

徐艳, 何重香, 周鑫, 潘丽, 叶啟发. 肾移植术后液体管理改善移植肾功能延迟恢复的研究进展[J]. 中华移植杂志(电子版), 2021, 15(06): 370-374.

Yan Xu, Chongxiang He, Xin Zhou, Li Pan, Qifa Ye. The progress of post-operative fluid management improves delayed graft function in kidney transplantation[J]. Chinese Journal of Transplantation(Electronic Edition), 2021, 15(06): 370-374.

移植肾功能延迟恢复(DGF)是肾移植术后常见并发症，其危险因素包括缺血时间、边缘供者及排斥反应等。近年来的研究认为，液体管理可能也是肾移植术后并发DGF的影响因素之一，合理有效的围手术期液体管理不仅能够降低肾移植术后DGF发生率、改善移植肾长期功能，还可降低受者围手术期死亡率。本文对围手术期肾移植受者液体管理、容量评估、液体不足及液体过载的治疗作一综述，以期为降低肾移植受者移植术后DGF发生率及改善预后提供参考。

关键词: 肾移植, 移植肾功能延迟恢复, 液体管理

Delayed graft function (DGF) is one of the common complications after kidney transplantation, the risk factors of DGF include ischemia time, edge donor and rejection and so on. Recent researches point out that fluid management may also be one of the risk factors, the incidence of DGF can be reduced and the long-term kidney function can be improved by successful perioperative fluid management, and the perioperative period mortality of recipients can also be reduced by the research progress of fluid management. This study reviewed the perioperative fluid management, the assessment of capacity, the treatments of fluid insufficient and overload of kidney transplant recipients, in order to reduce the incidence of DGF and improve the prognosis of recipientts.

Key words: Kidney transplantation, Delayed graft function, Fluid management
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